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The Journal of Neuroscience

Regional Excitatory-Inhibitory Balance Relates to Self-Reference Effect on Recollection via the Precuneus/Posterior Cingulate Cortex-Medial Prefrontal Cortex Connectivity June 18, 2025
Self-related representation can enhance perception and memory—a phenomenon known as the self-referential effect (SRE). While SRE has been linked to the activation of the default mode network (DMN), including the precuneus/posterior cingulate cortex (Pcu/PCC) and the medial prefrontal cortex (mPFC), the underlying neurochemical processes of DMN activations remain unclear. The balance of excitation and inhibition […]
He, Y., Sweatman, H., Thomson, A. R., Gracia-Tabuenca, Z., Puts, N. A., Chai, X. J.
Sequence Diversity and Encoded Enzymatic Differences of Monocistronic L1 ORF2 mRNA Variants in the Aged Normal and Alzheimer's Disease Brain June 18, 2025
Reverse transcriptase (RT) activity in the human brain has been inferred through somatic retroinsertion/retrotransposition events; however, actual endogenous enzymatic activities and sources remain unclear. L1 (LINE-1) retrotransposons bicistronically express ORF2, containing RT and endonuclease (EN) domains, and RNA-binding protein ORF1, together enabling L1 retrotransposition and contributing to somatic genomic mosaicism. Here, we assessed endogenous RT […]
Nicodemus, J., Liu, C. S., Ransom, L., Tan, V., Romanow, W., Jimenez, N., Chun, J.
Brain Topological Changes in Subjective Cognitive Decline and Associations with Amyloid Stages June 18, 2025
This study examined how amyloid burden affects structural and functional brain network topology in subjective cognitive decline (SCD), a risk condition for Alzheimer's disease (AD). Functional and structural brain networks were analyzed in 100 individuals with SCD and 86 normal controls (NC; both sexes included) using resting-state functional MRI and diffusion tensor imaging. Topological properties […]
Jiang, X., Zhang, M., Yan, C., Daamen, M., Boecker, H., Yue, F., Jessen, F., Hu, X., Han, Y.
The Functional Anatomy of Nociception: Effective Connectivity in Chronic Pain and Placebo Response June 18, 2025
Chronic pain presents a widespread and complex clinical puzzle, necessitating theoretical approaches. This study expands upon our evolving comprehension of the brain’s top-down information processing, encompassing functions such as prediction, expectation, and attention. These processes are believed to play a substantial role in shaping both chronic pain and placebo responses. To examine hierarchical cortical processing […]
Nara, S., Baliki, M. N., Friston, K. J., Ray, D.
Complex Impact of Stimulus Envelope on Motor Synchronization to Sound June 18, 2025
The human brain tracks temporal regularities in acoustic signals faithfully. Recent neuroimaging studies have shown complex modulations of synchronized neural activities to the shape of stimulus envelopes. How to connect neural responses to different envelope shapes with listeners’ perceptual ability to synchronize to acoustic rhythms requires further characterization. Here, we examine motor and sensory synchronization […]
Sun, Y., Michalareas, G., Ghitza, O., Poeppel, D.
Developmental Olfactory Dysfunction and Abnormal Odor Memory in Immune-Challenged Disc1+/- Mice June 18, 2025
Neuronal activity in the olfactory bulb (OB) drives coordinated activity in the hippocampal–prefrontal network during early development. Inhibiting OB output in neonatal mice disrupts functional development of the hippocampal formation as well as cognitive abilities. These impairments manifest early in life and resemble dysfunctions of the hippocampus and the prefrontal cortex that have been linked […]
Parbst, F., Kostka, J. K., Günther, A., Chen, Y.-N., Hanganu-Opatz, I. L., Bitzenhofer, S. H.

Google Chrome Blog

Introducing Google AI Ultra: The best of Google AI in one subscription May 20, 2025
Learn about Google AI Ultra, Google’s new AI subscription with the highest access to our most capable models and premium features.
New AI and accessibility updates across Android, Chrome and more May 15, 2025
In honor of Global Accessibility Awareness Day, we’re excited to roll out new updates across Android and Chrome, plus new resources for the ecosystem.
How we’re using AI to combat the latest scams May 8, 2025
Chrome and Android are releasing new AI-powered features to help combat online scams.
Use Lens to search your screen while you browse on iOS February 19, 2025
Use Google Lens to search your screen within the Google app or Chrome on iOS. Plus, AI Overviews are coming to more Lens queries.
5 ways Chrome Enterprise can secure your business every day February 13, 2025
Learn how Chrome Enterprise offers an extra layer of protection and control businesses can adapt to meet their needs.

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